Director I, siRNA Discovery Research Job at AbbVie, Cambridge, MA

  • AbbVie
  • Cambridge, MA

Job Description

Director-level scientific leader role overseeing siRNA discovery research and portfolio strategy across therapeutic areas. Responsible for advancing early-stage RNAi programs, directing a multidisciplinary team of 10+ scientists, and serving as strategic interface between discovery and therapeutic development teams.

Responsibilities

  • Define strategic roadmap for siRNA discovery platform aligned with therapeutic area priorities
  • Partner with therapeutic leaders to identify and prioritize high-value genetic medicine opportunities
  • Lead advancement of early-stage siRNA programs using milestone-based decision making
  • Serve as primary scientific and strategic interface between discovery and therapeutic areas
  • Drive scientific innovation by integrating emerging RNAi technologies and establishing collaborations

Requirements

  • Ph.D. in Molecular Biology, Biochemistry, Chemistry, or related field
  • 10+ years biotech or pharmaceutical industry experience
  • Deep expertise in siRNA therapeutics, oligonucleotide chemistry, or genetic medicines
  • Demonstrated track record leading discovery programs through decision milestones
  • Experience building and directly managing multidisciplinary scientific teams
  • Proven ability to influence across matrix organizations and establish external collaborations
  • Experience advancing siRNA or ASO programs into clinical development (preferred)

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